Craft in the City

Lung Cancer – Three New Biomarkers to Revolutionize Diagnosis and Treatment of Lung Cancer

Cancer is caused by environmental as well as generic factors. One of the leading environmental causes of cancer is smoking tobacco. The interaction between genes and smoking has been concluded to play a significant role in the development of lung cancer.

Breakthrough Research

Yafang Li, PhD, has been leading a team of researchers from Dartmouth in this field. The researchers have recently discovered three new single-nucleotide polymorphisms (SNPs). Essentially, SNPs are variations in human body’s DNA that are associated with a person’s susceptibility to developing certain diseases such as cancer.
The researchers used phenotype and genotype data from OncoArray Consortium to conduct the study. To improve their analysis, the researchers adopted a two-step strategy in a bid to reduce power often lost through ordinary gene environment interaction analysis.
According to the researchers, the three new SNPs may be used as biomarkers for scientists to use when categorizing individuals’ risks of developing lung cancer as a consequence of one’s genetics interactions with smoking. Overall, the SNPs are expected to improve the prognosis, diagnosis, and treatment of lung cancer in the near future. They may also set pace for research in other common forms of cancer associated with smoking and other environmental risks.

This research is reportedly the largest of its kind, according to Yafang. However, it is important to note that all the participants were of Caucasian origin. Considering that people from different races have variations in their genetic makeup, the results of this research may be largely limited only to the Caucasian population. However, the team of researchers is making plans to conduct similar research on people from other races in a bid to reduce any inconsistencies in findings. What’s more, the researchers promise to improve their findings as they collect more data on gene-smoking interaction.

A report detailing this research was published in the journal Carcinogenesis under the title Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk if Caucasian population.

About Eric Lefkofsky

Eric Lefkofsky is an entrepreneur and philanthropist with an interest in battling cancer. He is the founder of Groupon and a co-founder of Tempus.

Tempus is an upcoming health startup that is focusing on devising better ways to fight cancer. The firm claims to work with scientists and physicians to analyze patients’ genetic code in respect to molecular therapy. By collecting and analyzing genomic data, Tempus hopes to improve precision and personalization in the diagnosis and treatment of cancer.

Tempus is currently on lung, breast, and pancreatic cancer, but plans are underway to study other common types of cancer.

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Fabletics: Crowd Favorite

For the longest time, companies had the power to determine which brands were considered high-quality. Consumers relied on traditional advertising to determine their final purchases. Recently, there’s been a shift in consumer behavior. People are no longer trusting traditional advertisements and started trusting online reviews from fellow consumers.

These crowd-sourced reviews offer insight into the product or service’s true quality. Over the years, more people joined the review-centric movement, forcing companies to rethink their traditional marketing strategies. One company having no problem adjusting to this new craze is Fabletics. Fabletics is proving to be one of the more savvy brands.

Fabletics was founded on a premise that centered on personalized service. The brand uses a subscription mechanic and offers personalized recommendations for each of its members every month. That attention to detail is what put Fabletics on the map, allowing the brand to compete in a marketplace already dominated by several big-name household brands.

Over the past four years, Fabletics attracted over one million people to their membership program, many of which opted for the VIP membership. People seem to really love the on-trend fashion for affordable prices. Additionally, members receive numerous discounts on hundreds of items up to 50 percent off.

There’s also a personal flare about Fabletics that attracts millions of people. That personal touch comes from one of the brand’s co-founders: Kate Hudson. Kate Hudson is a renowned fashion icon and advocate for health and fitness. She saw Fabletics as an opportunity to help women look and feel their best.

For most activewear lines, it’s about being the most popular and most successful. For Hudson, it’s about America’s problem with health. She uses Fabletic’s fashion to inspire women to embrace active lifestyles at their own comfort level. It works best when people decided to become healthy on their own.

Kate Hudson learned early in life the power of inspiration. With the right encouragement, anyone can overcome any obstacle. Fabletics can best inspire women to embrace active, healthy life choices because Kate Hudson is inspired to help them. Her inspiration comes from her mother, who started her own foundation to help children learn mindfulness.

With that sort of role model, it’s no wonder why Hudson seems so fearless in her endeavor. Her desire to take America’s war against obesity will continue until she’s won.

Tony Petrello’s Outstanding Excellence In Business Leadership And Philanthropy

Tony Petrello has at one time been one of the highest paid CEOs in the US. He is in charge of Nabors Industries, a top-rated oil and gas firm incorporated in Bermuda with an operational hub in Houston, Texas. The humble man raked in over $60 million in annual income in 2014, catapulting him into the national spotlight. He has since effected policy reform at the company to align executive remuneration with business revenues and the views of investors.

For this reason, his income is now closely tied to the performance of the business. Under his leadership, the holding company has grown to employ more than thirty thousand people in the US. The firm operates more than five hundred oil and gas drilling rigs around the world. A native of Newark in New Jersey, Tony Petrello grew up to appreciate the compelling values of integrity and consistency.

He demonstrated a keen interest in math from an early age. His prowess in math earned him a scholarship to Yale University where he continued to impress the dons. He obtained an MBA in mathematics from the learning institution and then proceeded to Harvard Law School. Tony Petrello later worked as a Managing Partner of Baker & McKenzie, a boutique law practice based in New York.

His legal expertise and negotiating skills in business opened an opportunity for him to enter the oil and gas industry through the drilling conglomerate. He joined Nabors Industries in 1991 in the COO position. He was appointed the President the following year. He quickly rose through the ranks to the CEO position in 2011 and Chairman of the group the following year. He has proven himself as an influential business leader in the US corporate environment.

Together with his wife, they donate generously to numerous charities in the Houston area. Besides Nabors Industries, he also serves as a director of Stewart & Stevenson as well as Hilcorp Energy. He is also associated with the Texas Children’s Hospital where he is a member of the board. He supports research into neurological disorders affecting children at the institution.

The holding company operates numerous global subsidiaries such as Nabors Drilling, Robotic Drilling Systems, Partner Rentals, Peak USA Energy, Canrig and Ryan Energy among numerous others. Tony Petrello has built Nabors Industries to become the leading provider of land based drilling services in the world.

His latest move expands the firm’s footprint in the energy industry to solidify its leadership position. He is playing a pivotal role in the acquisition of Tesco Corporation, a Houston-based Canadian oilfield services provider targeting customers in the upstream line of the energy business.

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Bruno Fagali Steers Companies Upholding Business Ethics

Bruno Fagali is an experienced lawyer who lives in Rio de Janeiro. He got his first law degree at Pontifical Catholic University. After a few years of practicing, he went back to the University for masters in Administrative Law. This renowned legal officer also has another State Law postgraduate degree from the University of Sao Paulo.

After many years of studies, he applied for jobs at various law firms. Bruno Fagali started working in 2006. From these developing firms, he gained extra skills and knowledge on how to handle cases for clients. Little did he know that these experiences were preparing him for bigger and better opportunities? True to this statement, he got hired by Nova/SB. Till now he is serving as the manager of the law firm.

Most importantly, the experiences steered him towards starting his own law firm, FAGALI Advocacy. At the firm, they majorly offer legal advice pertaining to business matters. As a certified lawyer, he has focused his passions his areas of expertise to ensure that his clients are served well. His knowledge in business law has offered solutions to various entrepreneurs. Some of the legal advice he offers includes seeking help from professional lawyers. Many companies have sorted their court issues successfully because of him.

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Additionally, Bruno Fagali has provided the steps to follow in case any business is in need of an attorney according to The heads of the companies should contact reputable firms. In addition, they can seek recommendations from friends and relatives to which law firm they should consult with. Bruno Fagali’s greatest concern for his clients is that with an experienced business lawyer by their side, they can sail through any storm. This why consulting with lawyers they can trust is the best decision they can ever make.

Bruno Fagali has achieved real success since he started practicing as a certified lawyer. His experiences with clients have chiefly contributed to his growth as a lawyer and that of his law firm. Additionally, Bruno Fagali has impacted positively on the lives of many as well as contributing massively to the success of many businesses. Entrepreneurs hence have learned to uphold business ethics while improving the productivity of their businesses.

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Beneful Tops Other Dog Food Brands

Introduced into the consumer market by Nestle Purina Petcare in 2001, Beneful has remained to be one of the most popular brands of dog foods globally. The product has reportedly been ranked the 4th most popular brand and has since generated an average of $1.5 billion in revenue annually. According to Marketline, Beneful is among the leading revenue generating products at Nestle Purina Petcare.

Like the name suggest, Beneful is reported to simply mean ‘full of goodness’. The meaning has, however, been interpreted by many consumers as beneficial and healthful due to the product’s nutritional content. In a wider range of 8 different flavors, Beneful contains a mix of several nutritional ingredients including meats and vegetables.

The product resembles stew and comes in various forms including dry, wet and canned dog foods. The brand provides a unique packaging that can be used as a dog’s eating bowl. Benefulcommercial also offers a wide range of options for varying ages and health status.

A Test Of Purity

How You Know Your Holding Actual Gold. …


There’s no doubt about when you have the real thing.


If you don’t know about what gold looks and feels like, then it’s possible for you to be trick by fraud. The security you have is in the safety that exists in today’s market. The U.S. Money Reserve is a part of the protection during your transaction in bullion.


The feel of gold and its real purity are guaranteed by the U.S. Money Reserve. This agency is a great example of the firms that issue precious metals to the public. It’s important to use a reputable agency because of the potential you have with gold. The value of your initial investment has great potential to increase.


The Best Part Is Authenticity. It Makes You Lust.


There’s a pride that precious metal owners also have when holding real bullion. You can have the same experience and with great convenience. What you must invest in is the actual authenticity of your products. This authenticity is cherished as much as the coin and its rarity.


Having what you can express as actual gold in your hands makes a huge difference. This precious metal may not have an infinite lifespan in our society, but society has a very long way to go. The places these metals hold in society are for purposes in structure, organization and fair trade.


How To Verify The Quality Of Gold


There are steps you can take to verify the quality of your gold. These steps mean nothing until you find a reputable dealer. The dealer is often the issuer of quality, weight and certified bullion. This happens through a variety of measures. The most important business factor are buy-back guarantees.


These are basic guarantees placed on bullion products and because of purity. Agencies like U.S. Money Reserve offer buy-backs because the values of precious metals are stable in international markets. This U.S. firm is willing to buy-back because world governments continue to hold gold in reserve.


This competitive stance is placed in your hands and with this one U.S. agency.


OSI Growth Expands its Markets through Joint Ventures

OSI Group has a rich history and has a significant role in the food industry in the world. The Group produces various goods ranging from vegetables to beef to sandwiches, chicken, sauces, and pizza. It has its headquarters in a city in Illinois known as Aurora. The top leaders at OSI Group are David McDonald, the chief operating officer and president and Sheldon Lavin, the chief executive officer. The two senior leaders have seen the company grow to the extensive food processing and distributing company it is currently.

Some eco-friendly facilities enabled the Group to earn Leadership in Energy and Environmental Design certifications in 2014 and 2015. OSI Ostroda and Henan Best Foods have been certified because they achieved environmentally friendly operations. OSI Group later in 2016 established a new joint business in Germany. The company began cooperating with Edeka, a grocery store chain. It has become the largest supermarket in Germany. OSI Group created a development and research center in eastern China. It has also maintained similar plants in the US and Germany, which allows its employees to come up with personalized products.


OSI Group made a joint venture with GenOSI in the Philippines, which has continued to benefit the food processing company. It established a new processing plant in May 2017. The new facility deals with beef, chicken, and fish to eateries and food service companies. The plant has the capability of producing close to 51 million pounds annually. Fred Uytengsu, GenOSI’s president, praised the lasting partnership with OSI, while Sheldon Laving referred to the plant as a world-class facility.

Eastern Europe

OSI Group began constructing a new facility in 2012 in Poland. It had plans for replacing a nearby plant that started processing beef close to 20 years earlier. Their clients in Sweden, Slovakia, Poland, Finland, the Baltic States, and the Czech Republic are now ordering hamburgers from the new facility in Ostroda. The construction has a cost of over $30 million, and it has a maximum output of 25,000 tons. OSI also expanded presence in Hungary before 2012 ended by opening a chicken processing plant. The Group spent about $25 million to develop production and storage areas. The plant enlarged the Group’s capacity by 15,000 tons annually.


OSI Group has a significant presence in South Asia. It started its cooperation with Vista Processed Foods in 1995, a well-known supplier in India. It also opened a new facility in March 2012 to deal with the processing of frozen vegetables. The Madanapalle plant serves fast-food outlets and Indian stores. It also opened such a facility seven months later in Punjab, which supplies frozen and fresh vegetables serving India and clients in Middle Eastern countries.

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The American Education Sector Is In The Hands of Business Leader Betsy DeVos

Betsy DeVos’ bid to improve the American school system has attracted attention and criticism in equal measure. The public is following closely what the business leader and philanthropist is going to achieve in her role as the United States Secretary of Education. Betsy got her new job in the Trump administration because of her vast experience in the education sector working with charter and schools of choice. Before she got the post of cabinet secretary for education, Betsy had carried out extensive programs that afforded many students from marginalized communities access quality education.


On top of the agenda on Betsy DeVos’ master plan to revive the American education system is the privation of schools. A while back, Betsy DeVos did a personal assessment on how choice schools were helping students achieve their individual needs in education. This study was done at Holy Comforter and Florida High Schools. Such an initiative is in line with Betsy DeVos’ campaign for the popularization of choice schools and charter institutions. Betsy believes that community schools have a place in the modern curriculum and they should not be left behind when people are looking for wholesome solutions to problems in the society.


According to Betsy DeVos, we cannot expect excellent results if we continue relying on a curriculum that doesn’t address the needs of today. There needs to be a paradigm shift on how America handles her educational issues.


Betsy DeVos has been on the frontline in agitating for school vouchers, scholarships or grants to marginalized children and funding of charter schools. Before Betsy joined Trump’s administration, she devoted most of her time in charity work and engaging with families from marginalized regions.


Betsy DeVos wouldn’t have achieved much had she been on her own. The business leader enjoys the support of her husband Dick DeVos who is also actively involved in philanthropy. The couple has worked together on countless occasions to bring life-changing programs to the communities of Michigan. Betsy DeVos is the best example of how individuals can take a leading role in bringing change to the society. Her constant involvement with what is suitable for the American children has distinguished her as a woman of influence and change.


Not only has Besty succeeded in building an illustrious career in philanthropy, but she has also managed to create her space in the American politics. Betsy is committed to creating impact in the communities of Michigan and the entire nation at large.


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